Agitation

70.0 kgHome

Disclaimer

• All patients receiving chemical restraints / sedation should be closely monitored and frequently reassessed due to risk of excessive sedation and need for ventilatory support. • Anti-psychotics have risk of QT prolongation and subsequent cardiac arrhythmia. • Chemical restraints should only be used when verbal deescalation techniques have failed and the patient's behavior puts them or others at risk for harm.

Agitation medications

"B-52"

  • Benadryl 50 mg IM
  • Haloperidol 5 mg IM
  • Lorazepam 2 mg IM
Diphenhydramine 50 mg
50 mg/mL1 mL
Haloperidol 5 mg
5 mg/mL1 mL
Lorazepam 2 mg
2 mg/mL1 mL
4 mg/mL0.5 mL

"5 and 5"

  • Droperidol 5 mg IM
  • Midazolam 5 mg IM
Droperidol 5 mg
2.5 mg/mL2 mL
Midazolam 5 mg
1 mg/mL5 mL
5 mg/mL1 mL

"5150"

  • Haloperidol 5 mg
  • Lorazepam 1 mg
  • Diphenhydramine 50 mg
Haloperidol 5 mg
5 mg/mL1 mL
Lorazepam 1 mg
2 mg/mL0.5 mL
4 mg/mL0.25 mL
Diphenhydramine 50 mg
50 mg/mL1 mL

Haloperidol + Lorazepam

  • Haloperidol 5 mg IV/IM
  • Lorazepam 2 mg IV/IM
Haloperidol 5 mg
5 mg/mL1 mL
Lorazepam 2 mg
2 mg/mL1 mL
4 mg/mL0.5 mL

Pediatric weight-based dosing

DrugPediatricAdult
Midazolam IM/IN14.0 mg (0.2 mg/kg, max 10)5-10 mg IM
Ketamine IM280 mg (4 mg/kg, max 500)4-5 mg/kg IM
Olanzapine10 mg ODT/IM5-10 mg IM/ODT
Haloperidol3.5 mg IM (max 5)5-10 mg IM
Droperidol2.10 mg IM2.5-5 mg IM/IV