Fever

No patient weight set. Open Pediatric Weight, Age, Height, or Length Tape to enable dose calculations.
Antipyretics
DrugDoseInterval
Acetaminophen PO—q4-6h
Acetaminophen PR—q6h
Ibuprofen (>6 mo)—q6h
Fever workup by age
<28 d: full sepsis w/u, empiric Amp + Gent + Acyclovir. 29-60 d: Step-by-step / PECARN, +/- LP. >60 d well-appearing: source-directed.
Empiric antibiotics
  • Sepsis, meningitis

    IV/IM
    Adult: 1-2 g IV
    IV/IM• 100 mg/mL (reconstituted)• 100 mg/kg

    Meningitis dose 100 mg/kg; non-CNS 50 mg/kg

  • Neonatal sepsis, GBS

    IV
    Adult: 2 g IV q4-6h
    IV• 100 mg/mL• 50 mg/kg
  • Gram-negative coverage

    IV
    Adult: 5-7 mg/kg IV daily
    IV• 40 mg/mL• 2.5 mg/kg
  • Neonatal/pediatric HSV

    IV
    IV over 1 hr• 50 mg/mL• 20 mg/kg