Shock

70.0 kgHome

Initial bolus

20 mL/kg
1000 mL

Up to 60 mL/kg in first hour for septic shock

Empiric antibiotics

  • Ceftriaxone

    Sepsis, meningitis

    IV/IM
    Dose
    2000 mgMax
    Volume
    20.0 mL
    IV/IM• 100 mg/mL (reconstituted)• 100 mg/kg

    Meningitis dose 100 mg/kg; non-CNS 50 mg/kg

  • Vancomycin

    Sepsis, MRSA coverage

    IV
    Dose
    1000 mgMax
    Volume
    200 mL
    IV over 60+ min• 5 mg/mL diluted• 15 mg/kg

  • Cefepime

    Febrile neutropenia, sepsis

    IV
    Dose
    2000 mgMax
    Volume
    20.0 mL
    IV• 100 mg/mL• 50 mg/kg

Vasoactive support

DrugDoseUse
Epinephrine0.05-0.3 mcg/kg/minCold shock
Norepinephrine0.05-0.3 mcg/kg/minWarm shock
Dopamine5-10 mcg/kg/minBridge
Hydrocortisone2 mg/kg IV (max 100)Adrenal/refractory