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Neonatal Resuscitation

NRP-aligned dosing and equipment

Equipment
ETT size
3.5
ETT depth (lip)
9.0 cm
Suction catheter
8 Fr
UVC depth
10.0 cm
UAC depth (high)
18.0 cm
Laryngoscope
Miller 1
Vital Signs (term newborn)
  • • HR: 100–160 bpm (intervene if < 100 or > 180)
  • • RR: 30–60 breaths/min
  • • SBP ~ GA in weeks (e.g., 40 wk ≈ 40 mmHg) — MAP ≥ GA
  • • Temp (axillary): 36.5–37.5 °C
  • • Glucose: ≥ 45 mg/dL (treat < 40 in first 4h)
Gestational Age Estimates
GAAvg weightLength
24 wk600 g31 cm
28 wk1000 g37 cm
32 wk1700 g42 cm
36 wk2600 g47 cm
40 wk3400 g51 cm

Ballard exam (physical + neuromuscular score) recommended for accurate GA at delivery.

Emergency Medications
Umbilical Catheter
UVC depth
10.0 cm
UAC high
18.0 cm
UAC low
10.0 cm
Catheter size
5 Fr
  • • Emergency UVC: insert 2–4 cm until blood return
  • • Confirm UVC tip at IVC/RA junction (T8–T9 on CXR)
  • • UAC tip: high T6–T9 or low L3–L4 (avoid renal/mesenteric)
Oxygen Saturation Targets
Time after birthPreductal SpO₂
1 min60–65%
2 min65–70%
3 min70–75%
4 min75–80%
5 min80–85%
10 min85–95%

Probe on right hand/wrist (preductal). Start FiO₂ 21% term, 21–30% preterm.

APGAR Score
Sign012
AppearanceBlue/paleBody pink, ext blueAll pink
PulseAbsent< 100≥ 100
GrimaceNoneGrimaceCry/cough
ActivityLimpSome flexionActive
RespirationAbsentSlow/irregularStrong cry

Assess at 1 and 5 min. If < 7 at 5 min, repeat q5 min up to 20 min. APGAR does not guide resuscitation.

Crashing Neonate DDX (THE MISFITS)
  • T — Trauma (NAT, birth)
  • H — Heart disease (ductal-dependent CHD) → PGE1
  • E — Endocrine (CAH, hypoglycemia, thyroid)
  • M — Metabolic (Na/K/Ca, IEM, hypoglycemia)
  • I — Inborn errors of metabolism
  • S — Sepsis (GBS, E. coli, HSV)
  • F — Formula errors (over/under-dilution)
  • I — Intestinal catastrophe (NEC, malrotation/volvulus)
  • T — Toxins (maternal, environmental)
  • S — Seizures
Empiric workup: D-stick, CBC + cultures, BMP/Ca/Mg, lactate, ammonia, blood gas, CXR, UA, LP. Empiric ceftriaxone or amp + gent + acyclovir, D10 bolus, consider PGE1 if cyanosis unresponsive to O₂.
NRP Quick Reference
  • • PPV at 40-60 breaths/min if HR < 100 or apneic
  • • Compressions 3:1 with PPV if HR < 60 after 30s effective PPV
  • • Start with room air (term) or 21-30% O₂ (preterm)
  • • Epi 0.02 mg/kg IV/IO (0.06 mg = 0.6 mL of 0.1 mg/mL)
  • • Volume bolus NS 10 mL/kg (30 mL)
  • • D10 2 mL/kg for hypoglycemia (6.0 mL)