• Treatment of withdrawal should be guided by symptom severity (e.g., CIWA-Ar score).
• are first-line therapy. Use cautiously in patients with respiratory depression or hepatic dysfunction.
• Monitor airway, breathing, and hemodynamics closely.
Benzodiazepines
Adjuncts
• Thiamine 100 mg IV/IM before glucose to prevent Wernicke's encephalopathy.
• Folate 1 mg IV/PO daily.
• Multivitamin (banana bag).
• replacement if low.
• IV fluids for volume depletion.